JMIRx (jmirx.org) is a new journal series (launched end of 2019) and new type of journal, which we call "superjournals". The first published peer-reviews, author responses, and revised papers can be found at http://xmed.jmir.org .
Superjournals (a type of "overlay" journal) are sitting on top of preprint servers and offer peer-review and copyediting/archiving/indexing, thus do everything a "normal" journal does, except that authors no longer have to submit their manuscript to a journal - instead, our acquisition and review editors find the papers they want to publish and extend conditional offers of publication to interesting articles published in Preprint servers, as well as soliciting reviews and commentaries. In addition to the "editorial prospecting" workflow, authors can also self-nominate their existing preprints for publication (which is the equivalent to a traditional journal submission), without going through another submission process. If superjournals ask for revisions, these revisions are also uploaded to the Preprint server.
We see this as the future of publishing, as predicted 20 years ago in the year 2000:
Researchers could submit type-1 electronic papers [non peer-reviewed preprints] to preprint servers for discussion and peer-review, and journal editors and publishers would pick and bid for the best papers they want to see as ‘type-2 papers’ [version of record] in their journal.” 
We are currently launching the following superjournals:
- JMIRx|Med - sitting on top of the medRxiv preprint server and covering the subjects covered in medRxiv
- JMIRx|Bio - sitting on top of the bioRxiv preprint server and covering the subjects covered in bioRxiv
- JMIRx|Psy - sitting on top of the PsyArXiv preprint server and covering the subjects covered in PsyArXiv
In addition, manuscript submissions can be transferred from the JMIR preprint server and JMIR journals to JMIRx and vice versa.
How to submit (tentative process)
To submit a preprint to JMIRx, either submit a Preprint directly to JMIRx (and opt-in when you are asked to expose the submission on JMIR Preprints) or upload a Preprint to MedRxiv and then user the M2J (or here called M2JMIR) functionality at MedRxiv to submit the paper to the Journal of Medical Internet Research - you will then receive an email with a link to the JMIR submission form, where you must change the target journal to JMIRx.
No more endless submission forms (what we are working on)
We are working on this: Submission to a JMIRx superjournal will be as easy as filling in a 4-field form pointing to the URL of the Preprint.
Innovative peer-review models
Authors can select various modalities for peer-review, which include
- traditional narrative review reports
- annotation-based, crowdsourced reviews
- a "Preprint journal club" consisting of a videoconference session with experts and interested readers, which will be transcribed and form the basis for an author revision
Manuscript Marketplace: Transfer to other JMIR journals and COAP (Coalition of Open Access Journals)
After peer-review, a manuscript will be put on a manuscript marketplace and can either
- be rapidly published in JMIRx (accepted papers for JMIRx Med currently live on https://xmed.jmir.org/),
- or be published in a COAP partner journal
We put manuscripts and their peer-review reports on a manuscript marketplace, which currently consists of all JMIR journals and journals from other publishers who joined the COAP coalition. Editors of these participating journals can make offers to publish the peer-reviewed papers in their journals, often with a significant discount, and often with minimal or no further changes required.
Publication in the JMIRx-series of journals is always the "fallback" (JMIRx journals will ultimately be indexed and have impact factors etc).
JMIRx as free alternative to already accepted submissions to JMIR journals
NEW (2020): If you have an accepted paper in any JMIR journal, and you previously published your submission on JMIR Preprints or a preprint server such as MedRxiv, we can now offer transfer and rapid publication free of charge in JMIRx. Please contact the editorial office if you are interested in that option.
Library and national consortia partnerships
JMIRx is a diamond journal.
We do not charge authors.
We aspire to create more institutional memberships such as the University of California partnership, that enables faculty and students from all 10 UC campuses to publish free of charge in JMIRx (subject of reimbursement of US$1000 by UC for each article peer-reviewed and published in a JMIRx journal).
We call this "subscribe-to-peer-review / subscribe to Open Science" product "Plan P" (What is Plan P?).